Salt sensitivity-definition, prevalence and pathophysiology
The term salt-sensitivity is difficult to define in humans. An accepted method of assessing salt sensitivity was proposed by Weinberger et al.. which is based on the difference between the blood pressure after 7 days sodium depletion with a low NaCl diet (10 mmol / d) plus furosemide, followed by 2L saline infusion. Salt-sensitivity was defined as a difference of ≥ 10 mmHg between salt-depleted and salt-loaded states. Using these criteria, 73% of African-Americans with hypertension, and 56% of Caucasian hypertensive patients, were salt-sensitive. About one third of normotensive subjects under investigation were salt-sensitive.
Jens Titze
Department of Nephrology and Hypertension & Nikolaus-Fiebiger-Centre for Molecular Medicine, Gluckstr.6, 91054 Erlangen
国际会议
西安
英文
35-36
2008-12-01(万方平台首次上网日期,不代表论文的发表时间)