Long-term Outcomes of Acute Ischemic Stroke Patients Treated with Endovascular Thrombectomy
(0) Objectives: To determine the long-term outcome of acute ischemic stroke (AIS) patients after endovascular thrombectomy (ET),to identify risk factors for long-term unfavorable outcome,and to investigate differences between patients with large-artery atherosclerosis (LAA) and cardioembolism.Methods: This study is a prospective registry study of revascularization therapy for AIS in Xuanwu Hospital from December 2012 to April 2016.The long-term outcome was collected via telephone interview and/or clinic visits.Favorable outcome was defined as modified Ranks scale(mRS) scores 0-2,and unfavorable outcome was defined as mRS scores 3-6.The primary outcome was mRS at the time of assessment.Results: Eighty nine out of 99 AIS subjects with large artery occlusion in anterior circulation and treated with Solitaire FR were eligible for analysis.Median follow-up duration was 20 months (IQR 6-32),and 47 (53%) subjects achieved favorable outcome whereas 17 (19%) subjects were functional dependence and 25 (28%) subjects died.Independent predicators for long-term unfavorable outcome were baseline NIHSS score (OR: 1.22;95% CI 1.09-1.36;p=0.001) and symptomatic intracerebral hemorrhage (sICH) (OR: 25.14;95% CI 2.20-287.72;p=0.010).More subjects of LAA were treated with permanent intracranial stenting (22%vs.10%) as compared with those of cardioembolism.Subjects of cardioembolism are more likely to experience sICH (19%vs.8%) and die (32%vs.16%) as compared with those of LAA.Conclusions: Over half of AIS patients can achieve favorable long-term outcomes after ET.Higher baseline NIHSS scores and presence of sICH are independently associated with unfavorable outcome.Subjects of cardioembolism are more likely to experience sICH and die.
Wenbo Zhao Shuyi Shang Chuanhui Li Longfei Wu Jian Chen Haiqing Song Qingfeng Ma Hongqi Zhang Liqun Jiao Feng Ling Yuping Wang Jiangang Duan Wuwei Feng Xunming Ji
Department of Neurology, Xuanwu Hospital, Capital Medical University,Beijing, China Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China Department of Emergency, Xuanwu Hospital, Capital Medical University, Beijing, China Department of Neurology, Medical University of South Carolina,Charleston, USA
国际会议
北京
英文
104-109
2019-03-30（万方平台首次上网日期，不代表论文的发表时间）