The dynamic evaluation and efficacy of ultra-high sensitivity chromosomal instability detection in liver cancer treatment
(0) Purpose: To analyze the dynamic evaluation and efficacy of ultra-high sensitivity chromosome instability detection in liver cancer treatment.Method: Randomly selected 72 patients with liver cancer from September 20 to May 2019 in our hospital and through various chemical methods,we have come to understand the expression of MSI and mutant P53 protein in chromosome 17P of patients with liver cancer.Outcome: It can be seen from the experiment that there is no difference between the MSI and the patients gender(P>0.05).For the sudden P53 protein expression,there is no significant difference in each age of onset(P>0.05),but AFP is positive,because the positive expression rate of hepatoma mutant P53 protein was significantly higher than that of AFP negative liver cancer(P<0.05)and there was no significant difference between the expression of positive liver cancer mutant protein and negative(P>0.05),and there was also no comparability.Conclusion: There is no correlation between MSI and the pathogenesis of most HCC.The carcinogenic mechanism of P53 gene mutation in HCC does not pass the path of MSI pathology of the expression of P53 gene mutation will be different,and the difference in expression will be closely related to carcinogenic factors,so people should also gradually increase their research efforts to promote the treatment of the disease.
Liver cancer Ultra-high sensitivity chromosome Instability test Dynamic assessment healing efficacy
Dehong Yin Gaomiyang Liu Fei Shi Yijia Song Rong Lu
Peoples Liberation Army of China Joint Logistics Support Force No.920 Hospital,Childrens Hospital of Shanghai,Shanghai,China
国际会议
西安
英文
46-48
2019-08-23（万方平台首次上网日期，不代表论文的发表时间）