Synthesis and Biological Activity of a 3,5-Disubstituted-1,2,4-Oxadiazole Fungicide Containing 3-Pyrazole Group

摘要：

　　In order to develop a new compound with novel structure and bactericidal activity.A series of 3,5-disubstituted-1,2,4-oxadiazole compounds containing pyrazole group were designed and synthesized.Their structures were confirmed by 1H NMR and HRMS,their bactericidal activity were evaluated by against rhizoctonia solani,gibberella zeae,botrytis cinerea and physalospora piricola.Preliminary bioactivity test results indicated that compound I6 showed the highest bactericidal activity among them,the inhibition rates of compound I6 against the above four fungi were 87.56,88.69,86.38,89.78,respectively.

关键词： Pyridine Oxadiazole Bactericidal activity

作者: Mingming Zhang Huanqi Cui Junjun Han Liangzhong Xu

作者单位: China College of Chemistry and Molecular Engineering,Qingdao University of Science and Technology,Qi China College of Chemistry and Molecular Engineering,Qingdao University of Science and Technology,Qi

会议类型: 国际会议

会议名称: 2019 4th International Conference on Life Sciences, Medicine, and Health( 2019年第四届生命科学、医学和健康国际会议)(ICLSMH 2019)

会议地点: 西安

会议语种:英文

页码: 84-88

在线出版日期: 2019-08-23（万方平台首次上网日期，不代表论文的发表时间）