Study Progress in the Application of Bone Targeting Drugs for the Treatment of Osteoporosis
Belongs to the metabolic disease with the highest incidence rate.The middle-aged and elderly people are the main disease group.Osteoporosis may lead to an increased risk of fracture.Currently,the drugs for clinical treatment of OP mainly on drugs of inhibiting the bone resorption and promoting bone synthesis.With the gradual deepening of the research on the etiology and pathogenesis of OP,the bone targeting drugs such as cytokines,hormones and peptides have been widely used in clinical practice.All of them have certain curative effects,but there are limitations in the use of various drugs.It is important to find a bone targeting drug with strong bone-affinity and stable structure to improve the symptoms of bone loss in patients.Based on the above background,this paper summarizes the application of bone targeting drugs to OP,summarizes the mechanism and efficacy of various drugs,and concludes and prospects future application trends,hoping to provide more options for clinical drug use.
Osteoporosis Bone targeting drugs Study progress
Jian Wang Yan Duan Changpeng Xu Li Gong Yu Zhang Limin Cen Qiwen Sun
Inner Mongolia Autonomous Region Peoples Hospital Hohhot Inner Mongolia 010010 Guangdong Second Peoples Hospital,Hohhot,Inner Mongolia 510050,China Southern Medical University Guangzhou Guangdong 510050
国际会议
西安
英文
149-153
2019-08-23（万方平台首次上网日期，不代表论文的发表时间）