The Influence of DMAc Ratio in Sheath Fluid on the Diameters of Medicated Cellulose Acetate Nanofibers
Accurate manipulation of electrospun nanofibers diameter is highly sought after for realizing their functional performances.Different with traditional methods in reducing nanofiers size,the present job demonstrated that the compositions of sheath mixed solvent were able to exert a significant influence on the modified coaxial processes and correspondingly the final solid medicated nanofibers diameter.Scanning electron microscopic images showed that all the prepared ibuprofen-loaded cellulose acetate nanofibers had a linear morphology with few beads or spindles on them although they were prepared under a variable volume ratio of N,N-dimethylacetamide(DMAc)in the sheath mixture with acetone.The linear relationship between the medicated CA nanofibers diameter(D)and the volume ratio of DMAc in the sheath fluid(r)was D= 1013-685r,with a correlated coefficient of R2=0.9835.The strategy reported should also be useful for other electrohydrodynamic atomization methods for generating high quality micro-/nano-products in a controllable manner.
Coaxial electrospinning,Nanofibers,Cellulose acetate,Sheath fluid DMAc
Ziyun Gong Yutong Du Yutian He Anlong Yang Yaoyao Yang Dengguang Yu
School of Materials Science and Engineering,University of Shanghai for Science and Technology,Shanghai 200093,China
国际会议
合肥
英文
12-19
2019-06-29(万方平台首次上网日期,不代表论文的发表时间)