Gold nanoparticles-loaded hydroxyapatite composites guide osteogenic differentiation of human mesenchymal stem cells through Wnt/β-catenin signaling pathway

摘要：

Background:Precise control and induction of the differentiation of stem cells to osteoblasts by artificial biomaterials is a promising strategy for rapid bone regeneration and reconstruction.Purpose:In this study,gold nanoparticles(AuNPs)-loaded hydroxyapatite(HA-Au) nanocomposites were designed to guide the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells(hMSCs) through the synergistic effects of both AuNPs and HA.Materials and methods:The HA-Au nanoparticles were synthesized and characterized by several analytical techniques.

关键词： gold nanoparticles hydroxyapatite nanocomposites osteoblast differentiation bone regeneration

作者: Hang Liang Cao Yang

作者单位: Union hospital,Huazhong University of Science and Technology Tongji Medical College

会议类型: 国际会议

会议名称: The 7th International Conference on Smart Materials and Nanotechnology in Engineering (第7届智能材料与纳米技术国际会议)

会议地点: 哈尔滨

会议语种:英文

页码: 1-1

在线出版日期: 2019-09-20（万方平台首次上网日期，不代表论文的发表时间）