Design of Microneedles using Additive Manufacturing

摘要：

　　The aims of this study were to examine the feasibility of additive manufacturing for design of microneedle arrays and to evaluate the fabricated microneedle arrays.Arrays of microneedle design were created using computer aided design (CAD)software (Rhinoceros 5.0) and materialized by direct light processing (DLP) three dimensional printing (3DP) system.Three different slicing thickness (15,25, 40 micron) were used for manufacturing microneedles, and morphology, surface property and size of microneedles were evaluated by using digital microscopy and scanning electron microscopy (SEM).Various shape of microneedles with a height of 600 micron were fabricated, and hollow type microneedles with a minimum wall thickness of 100 micron can be produced using DLP system.These results highlight the possibility of 3DP systems for microneedles manufacturing.

作者: Sang-Byeong Song Seung-Jin Jung Jae-Min Lee Chan-Woo Song Yun-Seok Rhee

作者单位: College of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University,Jinju-si, Gyeongsangnam-do, 52828, Republic of Korea

会议类型: 国际会议

会议名称: The 4th Asian Symposium on Pharmaceutical Science and Technology & Enlarged Editorial Board Conference of the Asian Journal of Pharmaceutical Sciences (第四届亚洲药剂学论坛暨亚洲药物制剂科学杂志编委会扩大会议)

会议地点: 沈阳

会议语种:英文

页码: 76-78

在线出版日期: 2016-04-28（万方平台首次上网日期，不代表论文的发表时间）