A novel DACHPt loaded nanoparticle for enhanced safety and anti-tumor effect

摘要：

　　Polyethylene glycol modified hyaluronic acid (PEG-HA) can effectively encapsule dichloro(1,2-diamino-cyclohexane)platinum(Ⅱ)(DACHPt) via convalent bonds to form long-circulation and biocompatible nanoparticles for human non-small-cell lung carcinoma treatment.As a result, the nanoparticles exhibited remarkable anti-tumor effect both in vitro and in vivo.

作者: Lin Kang Zhonggao Gao

作者单位: State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, P.R.China

会议类型: 国际会议

会议名称: The 4th Asian Symposium on Pharmaceutical Science and Technology & Enlarged Editorial Board Conference of the Asian Journal of Pharmaceutical Sciences (第四届亚洲药剂学论坛暨亚洲药物制剂科学杂志编委会扩大会议)

会议地点: 沈阳

会议语种:英文

页码: 181-182

在线出版日期: 2016-04-28（万方平台首次上网日期，不代表论文的发表时间）