Tumour microenvironment-responsive lipoic acid nanoparticles for the targeted delivery of docetaxel to lung cancer

摘要：

To develop biocompatible,biodegradable and reduction-sensitive docetaxel (DTX)-loaded nanoparticles,we successfully crosslinked lipoic acid molecules to form lipoic acid nanoparticles (LANPs).These nanoparticles were prepared at an optimal cross-linking temperature and had small size (～110nm), negative zeta potential (～-35 mv)and excellent stability especially of antiaggregation

作者: Fenfen Gu Chuling Hu Zhongguang Tai Chong Yao Qingming Xia Chuai Gong Yuan Gao Shen Gao

作者单位: Department of Pharmaceutics, Changhai Hospital, Second Military Medical University, Shanghai 200433, China

会议类型: 国际会议

会议名称: The 4th Asian Symposium on Pharmaceutical Science and Technology & Enlarged Editorial Board Conference of the Asian Journal of Pharmaceutical Sciences (第四届亚洲药剂学论坛暨亚洲药物制剂科学杂志编委会扩大会议)

会议地点: 沈阳

会议语种:英文

页码: 235-235

在线出版日期: 2016-04-28（万方平台首次上网日期，不代表论文的发表时间）