The Preparation of Enteric Press-coated Tablets of Mesalamine
The purpose of this study is to develop enteric press-coated tablets of mesalamine which have a release time lag of 4h, make the amount of drug reached the colon is improved, enhance the therapeutic effect of the drug.Finally, the ratio of HPC-L with MCC was 6:4, the amount of coating material was 240mg, the ratio of upper and lower coating layer was 1:1, the tablet diameter was 9mm.The compression coated tablets have a lag time of about 2h in simulated intestinal fluid.
Liuying Di Caixia Wang Hongyu Piao Meijuan Zou*
Department of Pharmaceutics School of Pharmacy Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang, 110016, China
国际会议
沈阳
英文
265-266
2016-04-28(万方平台首次上网日期,不代表论文的发表时间)