Dynamic enhancement effect of amphiphilic enhancers on the transdermal penetration of flurbiprofen: enhancing kinetics and molecular mechanism
The dynamic enhancement effect of the enhancers and the molecular mechanism of the phenomena were explored in this study.As a result,the enhancing activity of these enhancers increased fast primarily, then kept at a stable level, and decreased finally.The dynamic behaviors were decided by the molecular structures of the amphiphilic enhancers through their varied effects of the enhancers on the stratum corneum (SC)intercellular lipid.
Xiaochang Liu Liang Fang
Department of Pharmaceutical Science, School of Pharmacy, Shenyang Pharmaceutical University,103 Wenhua Road, Shenyang, Liaoning, 110016, China
国际会议
沈阳
英文
304-305
2016-04-28(万方平台首次上网日期,不代表论文的发表时间)