Peptide-labeled Near-infrared Fluorescent Magnetic Thermosensitive Liposomes Loading Doxorubicin

摘要：

　　One of the most efficient methods to treat cancer is the target delivery system of anticancer drugs.To achieve this goal, we designed a kind of multi-functional liposomes composing of doxorubicin (DOX), arginine-glycine-aspartic-serine acid sequence (RGDS), near-infrared CdSeTe quantum dots (CdSeTe QDs) and Fe3O4 nanoparticles.Natural phosphoiipids were used to prepare RGDS labeled near-infrared fluorescent magnetic thermosensitive liposomes carrying doxorubicin (RGDS-NFMTSLs-DOX).RGDS-NFMTSLs-DOX could release DOX, when they are triggered by heating from magnetic nanoparticles under an AC magnetic field.Meanwhile, RGDS-NFMTSLs-DOX was superbly suitable for real-time tracing of liposomes in vivo.

作者: Zhenzhen Li Qiyi Zhang Huaying Huang Qiang Zhao

作者单位: College of Chemical Engineering, Sichuan University, Chengdu, China

会议类型: 国际会议

会议名称: The 4th Asian Symposium on Pharmaceutical Science and Technology & Enlarged Editorial Board Conference of the Asian Journal of Pharmaceutical Sciences (第四届亚洲药剂学论坛暨亚洲药物制剂科学杂志编委会扩大会议)

会议地点: 沈阳

会议语种:英文

页码: 365-366

在线出版日期: 2016-04-28（万方平台首次上网日期，不代表论文的发表时间）