Comparison of Ion Exchange Fiber and Resin in Liposomes Transmembrane Gradient Establishment and Entrapment Efficiency Determination
To compare the effect of ion exchange fiber and ion exchange resin in liposomes transmembrane gradient establishment and entrapment efficiency determination, the liposomes prepared by pH gradient method, while cation exchange fiber/resin mini-column recovery and resolution were investigated.Results showed that entrapment efficiency increaced when anion exchange fiber was used to remove the external phase substances and establish the transmembrane gradient comparing with resin.Simultaneously, the recovery and resolution of cation exchange fiber were higher than resin.Showing that ion exchange fiber have more advantage to set up the liposomes transmembrane gradient and evaluate the entrapment efficiency.
ion exchange fiber ion exchange resin liposomes entrapment efficiency
Le Kang Yanzhi Song Qiao Gou Yue Liu Pengpai Li Huan Wang Yihui Deng Xinrong Liu
College of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, P.R.China
国际会议
沈阳
英文
367-369
2016-04-28（万方平台首次上网日期，不代表论文的发表时间）