Polymeric Complex of Procyanidin and PVP-VA64 for Taste Masking of Grape Seed Extract

摘要：

　　Polyvinylpyrrolidone copolymer (PVP-VA64)was selected as the carrier macromolecular material to form a novel polymeric complex with proanthocyanidin (pAC), the most abundant active ingredients in the grape seed extract, in order to mask the unpleasant sour and astringent taste of the extract and the preparations containing it, and the chewable tablets containing grape seed extract were prepared.DSC and FTIR methods were used to explore any interactions between PVP-VA64 and procyanidin to verify the complexation mechanism.Optimum taste masking effect was obtained via the complexation of procyanidin with PVP-VA64.However, further studies are still need to be carried out to determined in-depth taste-masking mechanism.

作者: Hui-lin Chen Rong-xue Wang Shao-ning Wang Yi-hui Deng Hui Xu

作者单位: School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, P.R.China School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, P.R.China

会议类型: 国际会议

会议名称: The 4th Asian Symposium on Pharmaceutical Science and Technology & Enlarged Editorial Board Conference of the Asian Journal of Pharmaceutical Sciences (第四届亚洲药剂学论坛暨亚洲药物制剂科学杂志编委会扩大会议)

会议地点: 沈阳

会议语种:英文

页码: 385-386

在线出版日期: 2016-04-28（万方平台首次上网日期，不代表论文的发表时间）