Age-dependent neurodegeneration and symptoms in a transgenic pig model of spinocerebellar ataxia type 3
Spinocerebellar ataxia type 3 (SCA3) is caused by a CAG repeat expansion in the ATXN3 gene, which encodes for ataxin-3 protein containing an expanded polyglutamine (polyQ).
transgenic pig spinocerebellar ataxia type 3 neurodegeneration cerebellum
Sen Yan Zhuchi Tu Quanmei Yan Xueyan Zhang Dazhang Bai Caijuan Li Yingqi Lin Zhaoming Liu Yu Zhao Shihua Li Liangxue Lai Xiao-Jiang Li
Ministry of Education CNS Regeneration Collaborative Joint Laboratory, Guangdong-Hongkong-Macau Inst Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, South China Institute fo College of Life Science and Technology, Jinan University, Guangzhou, Guangdong Province, China Ministry of Education CNS Regeneration Collaborative Joint Laboratory, Guangdong-Hongkong-Macau Inst
国际会议
广州
英文
66-66
2018-07-26(万方平台首次上网日期,不代表论文的发表时间)