Why and how does light therapy offer neuroprotection in Parkinsons disease?
Red and infrared light (λ=600-1,070 nm) therapy, known also as photobiomodulation, has been reported to offer neuroprotection and to improve locomotor behaviour in animal models of Parkinsons disease, from rodents to non-human primates (Rojas and Gonzalez-Lima, 2011;Hamblin, 2016;Johnstone et al., 2016).The neuroprotective aspect of this therapy is particularly relevant;the saving of neurons that would normally die as a result of the parkinsonian degeneration, is without doubt, the holy-grail for this, and indeed all other neurodegenerative disorders.The stage is set for translation of light therapy to human patients and there is much hope for beneficial outcome.In this perspective article, I would like to consider two major issues of light therapy that relate to its neuroprotective function, issues that have intrigued many scientific colleagues, together with the wider community.
John Mitrofanis
Department of Anatomy F13, University of Sydney, Sydney,Australia
国际会议
广州
英文
168-169
2018-07-26（万方平台首次上网日期，不代表论文的发表时间）