Patterns of carbohydrate binding modules of cellulase under visualization

摘要：

　　Cellulase is one of most important enzymes in biotechnology,and is generally structured in multiple domains,i.e.signal domain,catalytic domain,carbohydrate binding module(CBM)and linker.The CBM plays crucial roles in cellulosic hydrolysis including proximity effect,targeting,disrupting and amorphogenesis,and thus facilitates the association of soluble cellulases with insoluble cellulose.CBM can be classified into 81 CBM families according to their sequence similarity or into three types of CBMs according to their high-resolution structural similarity.Although not many studies have been directed to the visualization of CBMs,it is necessarily important to review different visualization studies on CBMs at both meso-and nano-scale in order to understand the general patterns of CBMs under visualization.In this mini-review,special attention is also placed on CBMs adsorption,space occupation and accessibility to cellulose surface and lattice face as well.At the end of this review,we raised three questions,which are worthy studying in future.

关键词： Carbohydrate binding module Cellulase Cellulose Microscopy Visualization

作者: Shaomin Yan Guang Wu

作者单位: State Key Laboratory of Non-Food Biomass and Enzyme Technology,National Engineering Research Center for Non-Food Biorefinery,Guangxi Key Laboratory of Bio-refinery,Guangxi Academy of Sciences,98 Daling Road,Nanning,Guangxi,530007,China

会议类型: 国际会议

会议名称: The 10th International Conference on Green Composites(第十届绿色复合材料国际会议)

会议地点: 福建泉州

会议语种:英文

页码: 1-12

在线出版日期: 2018-11-07（万方平台首次上网日期，不代表论文的发表时间）