Study on the Efficacy Evaluation of Oral Sequential Tamoxifen in Postmenopausal Women with Hormone-dependent Breast Cancer
(0) 135 breast cancer patients admitted to the Third Affiliated Hospital of Qiqihar Medical College since 2013.Inclusion criteria for patients with early surgical resection and complete pathology.There was complete immunohistochemical data,and the immunohistochemical SP method confirmed ER positive and/or PR positive.All the 135 patients in this group were female,aged 47-75 years old,with an average of 57.6 years old.All of them were stage II breast cancer patients,and all underwent radical mastectomy.All of them were confirmed to be estrogen receptor positive by immunohistochemistry.All are women.All the hormones were verified in the menopause.After grouping,the treatment group 1 was treated with 2.5 mg of letrozole.After one year of treatment,the patient was switched to oral tamoxifen 10 mg twice a day.Treatment group 2 oral administration of letrozole 2.5 mg,once a day treatment,every three months.RESULTS: The 5-year local recurrence rate was 13.8%in the treatment group 1 and the distant metastasis rate was 8.2%.The treatment group 2 was 10.4%and 10.4%,respectively.There was no significant difference in efficacy between treatment group 1 and treatment group 2.
Sequential tamoxifen tablets breast cancer efficacy
Na Li Yahua Sun Sheng Zhao Haiou Liu Kun Zhao
The Third Affiliated Hospital of Qiqihar Medical University,Qiqihar,Heilongjiang,161000
国际会议
重庆
英文
53-56
2018-11-08（万方平台首次上网日期，不代表论文的发表时间）