MCR-1.6, a New MCR Variant Carried by an IncP Plasmid in a Colistin-Resistant Salmonella enterica Serovar Typhimurium Isolate from a Healthy Individual

摘要：

　　In this study, we report a novel mcr-1 gene variant, named mcr-1.6,carried by an IncP plasmid in a colistin-resistant Salmonella enterica serovar Typhimurium isolate from a healthy person.Compared with mcr-1, the mcr-1.6 gene contains two single-nucleotide polymorphisms, one of which results in an arginine to histidine variation (Arg536→His).The plasmid carrying the mcr-1.6 gene was designated pMCR1.6_P053 and is similar to a recently discovered mcr-1-bearing plasmid found in Klebsiella pneumoniae.

关键词： colistin resistance MCR-1.6 IncP plasmid Salmonella enterica serovar Typhimurium

作者: Xin Lu Yongfei Hu Ming Luo Haijian Zhou Xiaoxun Wang Yu Du Zhenpeng Li Jialiang Xu Baoli Zhu Xuebin Xu Biao Kan

作者单位: State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communica CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Aca Yulin Center for Disease Control and Prevention, Guangxi, China State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communica School of Food and Chemical Engineering, Beijing Technology and Business University, Beijing, China Department of Microbiology, Shanghai Municipal Center for Disease Control and Prevention, Shanghai,

会议类型: 国际会议

会议名称: 2018细菌耐药性威胁与应对研讨会

会议地点: 北京

会议语种:英文

页码: 96-100

在线出版日期: 2018-03-29（万方平台首次上网日期，不代表论文的发表时间）