Characterization of a Multiresistant Mosaic Plasmid from a Fish Farm Sediment Exiguobacterium sp.Isolate Reveals Aggregation of Functional Clinic-Associated Antibiotic Resistance Genes

摘要：

The genus Exiguobacterium can adapt readily to, and survive in, diverse environments.Our study demonstrated that Exiguobacterium sp.strain S3-2, isolated from marine sediment, is resistant to five antibiotics.The plasmid pMC1 in this strain carries seven putative resistance genes.We functionally characterized these resistance genes in Escherichia coli, and genes encoding dihydrofolate reductase and macrolide phosphotransferase were considered novel resistance genes based on their low similarities to known resistance genes.

作者: Jing Yang Chao Wang Jinyu Wu Li Liu Gang Zhang Jie Feng

作者单位: State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Institute of Genomic Medicine, Wenzhou Medical College, Wenzhou, Zhejiang, China

会议类型: 国际会议

会议名称: 2018细菌耐药性威胁与应对研讨会

会议地点: 北京

会议语种:英文

页码: 226-232

在线出版日期: 2018-03-29（万方平台首次上网日期，不代表论文的发表时间）