ADSORPTION CHARACTERISTICS OF BILE ACID TO HYDROPHOBIC CATIONIC MICROFIBRILLATED CELLULOSE(MFC)
One of the ways to regulate the cholesterol level in the blood is to use bile acid adsorbent in the gastrointestinal tract.In this study,hydrophobic cationic microfibrillated cellulose(HCMFC)samples were produced by introducing quaternary ammonium groups with different alkyl chains,and the adsorption of bile acid,in vitro was determined.The results showed that the good adsorption behavior of the HCMFC was depending on the cationic charge density and the lengths of its alkyl substituent,the adsorption capacity for the HCMFC with a C16 alkyl substituent,was approximately 50%of that of Cholestyramine.It was found that the Langmuir isotherm was the best correlation for the adsorption of sodium cholate onto the cationic microfibrillated cellulose(CMFC)with a C1 alkyl substituent,and the Temkin model well fitted with the adsorption isotherm results of sodium cholate onto the HCMFC with a C16 alkyl substituent.The implication of the present study is that the modified MFC is a potential bile acid adsorbent.
Xuhai Zhu Yangbing Wen Yonghao Ni
Tianjin Key Laboratory of Pulp and Paper,Tianjin University of Science & Technology,Tianjin 300457,C Tianjin Key Laboratory of Pulp and Paper,Tianjin University of Science & Technology,Tianjin 300457,C Tianjin Key Laboratory of Pulp and Paper,Tianjin University of Science & Technology,Tianjin 300457,C
国际会议
第五届制浆造纸新技术国际研讨会(ISETPP)暨第三届国际造纸与环境学术大会(IPEC)
广州
英文
1-4
2016-11-07(万方平台首次上网日期,不代表论文的发表时间)