Preparation and Hypolipidemic Activities for Rats of partially deacetylated α-chitin nanofibers
In this study,chitin nanofibers(DEChN)were prepared by partial deacetylation with 30-35 wt%NaOH at 90 ℃ for about 2-4 h and the successive disintegration in water at pH 3-4.The average width and length of as-prepared nanofibers was 10 nm and several microns,respectively.To further study the biochemical properties of DEChN,chitin nanofibers dispersions was investigated in male Kunming(KM)rats to evaluate the hypolipidemic effects.Male rats were separated into five groups,i.e.a normal diet group,a high fat diet group,DEChN treated groups with three different doses of chitin nanofiber dispersions.Chitin nanofiber dispersions significantly decreased body weight gain and reduced the lipid level in plasma.The results suggested that chitin nanofibers reduced the absorption of dietary fat and cholesterol in vivo and could effectively improve hypercholesterolemia in rats.
Wenbo Ye Ke Zheng Jie Jiang Liang Liu Rong Wang Lijun Zhang Yimin Fan
Jiangsu Key Lab of Biomass-based Green Fuel & Chemicals,College of Chemical Engineering,Nanjing Forestry University,Nanjing 210037,China
国际会议
第五届制浆造纸新技术国际研讨会(ISETPP)暨第三届国际造纸与环境学术大会(IPEC)
广州
英文
1-5
2016-11-07（万方平台首次上网日期，不代表论文的发表时间）