Nanodiamond for Structural Biomimetic Scaffolds

摘要：

　　Bio-mechanically active scaffolds for tissue engineering combining hydrophilic polymeric matrix and nano-diamond fillers properties are presented and discussed in this paper.The resulting scaffolding materials revealed remarkable mechanical and biological properties to be exploited in advanced biomedical applications.The novel hybrid material is based on 2 and 5 volume % of detonation nano-diamond particles in a hydrophilic poly-(hydroxylethyl-methacrylate) matrix.According to its mechanical and biological properties, the nanocomposite shows a hybrid nature.The base analytical procedures for the preparation of the hybrid nano-composites and some preliminary mechanical characteristics are presented.The proposed hybrid system has been considered for potential biomimetic, osteoconductive and osteoinductive scaffolds application in bio-mechanically active bone scaffolds for osteoblast, and stem cell differentiation and growth.These more rigid hybrid nano-composites are predicted to possess improved mechanical strength overcoming the mechanical weaknesses of traditional hydrogels clinically utilized for bone regeneration.

关键词： Hybrid Nano-Composites Biomaterials Bioactive Scaffolds Bioengineering

作者: Raffaella Aversa Relly Victoria V.Petrescu Florian Ion T.Petrescu Antonio Apicella

作者单位: Advanced Material Lab, Department of Architecture and Industrial Design, University of Campania Luig Transport Traffic and Logistics Department, Bucharest Polytechnic University, Bucharest, Romania Theory of Mechanisms and Robots Department, Bucharest Polytechnic University, Bucharest,Romania

会议类型: 国际会议

会议名称: 第四届薄膜技术与应用国际会议(TFTA2018)

会议地点: 三亚

会议语种:英文

页码: 6-17

在线出版日期: 2018-01-13（万方平台首次上网日期，不代表论文的发表时间）