LGL (luxS-gmk-ldh) pathway may exerts a role in regulating Streptococcus.bovis lactate fermentation
Introduction Streptococcus bovis often predominates in the rumen when ruminants are fed a high concentrate diet,generally leads to an increase in lactate production in the rumen, which causes a drop in ruminal pH and contributes to the progress of rumen acidosis (Russell and Hino, 1985).To date, its fermentation pattern is dictated mainly by pH and substrate concentration (Chen et al., 2016).But in Asanuma and Hinos study (2002), we found that the proportion of lactate produced in S.bovis increased with the increasing of growth rate.Apart from it, Asanuma et al.(2004) also suggested that the expression of the luxS gene that encodes LuxS autoinducer 2 (AI-2) synthase in S.bovis declined with the decrease of growth rate.Since AI-2 operates as a universal quorum sensing (QS) system for many bacteria, it may control the expression of genes involved in metabolic pathways (An et al., 2014;Goo et al., 2015).We hypothesized that the luxS may regulate S.bovis lactate fermentation.The purpose of this study is to clarify how luxS is involved in the control of lactate fermentation in S.bovis by using bioinformatics method.
L.M.Chen Y.Z.Shen F.F.Zhao J.Sun H.R.Wang M.Z.Wang
Laboratory of Metabolic Manipulation of Herbivorous Animal Nutrition, College of Animal Science and Technology, Yangzhou University, Yangzhou, 225009, P.R.China
国际会议
The 5h International Symposium on Dairy Cow Nutrition and Milk Quality(第五届“奶牛营养与牛奶质量国际研讨会)
北京
英文
263-267
2017-05-05（万方平台首次上网日期，不代表论文的发表时间）