Feeding a high concentration diet induces unhealthy alterations in the composition and metabolism of ruminal microbiota and host response in a goat model
Introduction Feeding a HC diet for a short-term can induce the ruminal disturbance, a local inflammatory response in the ruminal epithelium, and even the systemic inflammation (Hook et al., 2011).However, information regarding the effects of long-term feeding HC diet on ruminal bacteria composition, metabolism, and the response of the epithelial cells has not been reported in ruminants.In this study, we used a combination of the 454 bar-coded pyrosequencing strategy and the gas chromatograph mass spectrometer (GC-MS)technique to investigate the effects of feeding a HC diet for short-and long-term on the alterations in ruminal microbiota and their metabolites, using goats as a model.Moreover, the relationships between microbiota abundance, ruminal metabolites, and genes expression related to host cells function were also analyzed in the present study.
Canfeng Hua jing Tian Ping Tian Rihua Cong Yanwen Luo Yali Geng Shiyu Tao Yingdong Ni Ruqian Zhao
Key Laboratory of Animal Physiology & Biochemistry, Ministry of Agriculture, Nanjing Agricultural Un College of Veterinary Medicine, Northwest A & F University, Yangling, Shannxi, China
国际会议
The 5h International Symposium on Dairy Cow Nutrition and Milk Quality(第五届“奶牛营养与牛奶质量国际研讨会)
北京
英文
276-278
2017-05-05（万方平台首次上网日期，不代表论文的发表时间）