Effects of retinoic acid on gene expression related to milk fat and protein synthesis in bovine mammary epithelial cells
Introduction Bovine mammary epithelial cells (BMEC) have been used as a model system for studying lactation and testing mammary tissue-specific expression vectors (Zavizon et al., 1996), as well as for the production of bioactive substances and target proteins with the mammary tissue-specific casein promoter (Brophy et al.,2003).Retinoic acid (RA) is a lipid-soluble signaling molecule derived from vitamin A (VA) that regulates a diverse array of biological processes, including celluar proliferation (purup et al.., 2001), differentiation and apotosis.We have known RA could regulate many kinds of genes, and could enhance antioxidant defense system and immune function (Jin et al., 2014).However, there is controversy about the effects of RA on milk performance and limited research concentrated on the influence of RA on milk fat and protein synthesis.Thus, our assay was conducted to investigate the effects of RA on milk fat and protein synthesis via detecting related genes expressions.
Y.Liu H.Y.Shi S.M.Yan B.L.Shi X.Y.Guo
College of Animal Science, Inner Mongolia Agricultural University, Zhao wu da Road306, Saihan District, Hohhot 010018, P.R.China
国际会议
The 5h International Symposium on Dairy Cow Nutrition and Milk Quality(第五届“奶牛营养与牛奶质量国际研讨会)
北京
英文
409-410
2017-05-05（万方平台首次上网日期，不代表论文的发表时间）