Diketopyrrolopyrrole-Based Therapeutic Nanoparticles for Photoacoustic Imaging Guided Phototherapy
Comparing to conventional therapeutic methods for cancer (such as surgery, chemotherapy, radiotherapy), photothermal therapy (PTT) and photodynamic therapy (PDT) are two main noninvasive phototherapies due to the low side-effects, high selectivity and effectiveness1.PTT and PDT are usually induced by near-infrared (NIR) light then the excited agents inside tumor can generate heat or reactive oxygen species (ROS) to kill tumor cells.Photoacoustic imaging (PAI) is non-invasive and non-ionizing imaging modality with high selectivity and deep penetration2.PAI guided PTT or PDT would be extraordinary beneficial to precise tumor treatment.To realize this ambition, a therapeutic agent, possessing high photothermal conversion efficiency and/or efficient ROS generation as well as PAI effect, good biocompatibility and ability to target tumor, is highly desired.
DONG Xiaochen HUANG Wei
Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing Tech University (NanjingTech), 30 South Puzhu Road, Nanjing 211816, China
国际会议
the 2016 International Seminar on Advanced Materials Research(2016先进材料研究国际研讨会)
昆明
英文
121-121
2016-10-14（万方平台首次上网日期，不代表论文的发表时间）