Preparation and Characteristics of Fragrance Loaded Silk Fibroin Microspheres

摘要：

　　Fragrances are valuable ingredients that are used in food, textile, daily use chemical products and medical supplies, etc.However, as a kind of volatile small molecule compounds,fragrances are often sensitive to environmental factors, such as light, oxygen, temperature and humidity, etc.Silk fibroin (SF) is a naturally derived protein that can be used to prepare biomaterials with excellent mechanical properties, biocompatibility and biodegradability.In the present work, through addition of polyethylene glycol (PEG) and fragrance to silk solution,fragrance loaded silk fibroin microsphereswere prepared.Citral, beta-ionone and myrcene,representing aldehyde, ketone and hydrocarbon respectively, were used as model fragrances.The morphology, size distribution, secondary structure, loading capability and thermal stability were characterized by scanning electron microscopy (SEM), dynamic light scattering (DLS), Fourier transform infrared spectroscopy (FT-IR) and thermal gravimetric analysis (TGA).The loadings of citral-SFMSs, beta-ionone-SFMSs and myrcene-SFMSs were approximately 36%, 24% and 23%,respectively.The encapsulation efficiencies were approximately 73%, 48%, and 45%, respectively.The fragrance loaded silk fibroin microspheres had good thermostability.Compared to pure fragrances, the silk-encapsulated fragrances showed more sustained release (> 2 weeks), likely due to the high content of silk β-sheet structure.

关键词： citral beta-ionone myrcene silk fibroin microsphere

作者: Wenjun Guo Xiaoqin Wang David Kaplan

作者单位: National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou 215123

会议类型: 国际会议

会议名称: The 9th China International Silk Conference (ISC2016)(第九届中国国际丝绸会议)

会议地点: 广西宜州

会议语种:英文

页码: 240-249

在线出版日期: 2016-09-09（万方平台首次上网日期，不代表论文的发表时间）