Ultrasensitive electrochemical Ochratoxin A aptasensor based on CdTe quantum dots functionalized graphene/Au nanocomposites and magnetic separation
Ochratoxin A (OTA) is one of the most toxic food contaminant mycotoxin,which can cause nephrotoxicity,teratogenicity,and carcinogenicity activity.Here an ultrasensitive electrochemical aptasensor for OTA was successfully fabricated.This aptasensor was constructed by combining nanocomposites of gold nanoparticles (AuNPs) functionalized silica-coated iron oxide magnetic nanoparticles (mSiO2@Au) and cadmium telluride quantum dots (CdTe QDs) modified graphene/AuNPs nanocomposites (GAu/CdTe).The as-prepared aptasensor exhibited a wide linear range (0.2 pg mL-1-4 ng mL-1),and an extremely low detection limit of 0.07 pg mL-1 (S/N=3).This work provides a novel strategy for the ultrasensitive detection of various target molecules and would have great potential in food safety monitoring and clinical diagnosis.
Ochratoxin A Aptamer Nanocomposites Electrochemistry
Nan Hao Ling Jiang Jing Qian Kun Wang
School of Chemistry and Chemical Engineering,Jiangsu University,Zhenjiang 212013,PR China School of Chemistry and Chemical Engineering,Jiangsu University,Zhenjiang 212013,PR China;Key Labora
国际会议
南京
英文
332-338
2016-12-23（万方平台首次上网日期，不代表论文的发表时间）