Construction of visible light-induced renewable electrode for monitoring of living cells
Ultraviolet (UV) light-induced photocatalysts have been utilized to construct renewable electrode to solve the problem of electrode fouling and passivation.However,considering the damages of UV irradiation to environments and biosystems,it is of great significance to develop and apply visible light-induced photocatalysts for biosensing.But for intrinsic visible light photocatalysts,the high electron-hole recombination rate results in the poor photocatalytic performance.Herein,we design the poly(3,4-ethylenedioxythiophene) (PEDOT)-modified TiO2/ CdS nanocomposites electrode,which can be efficiently renewed under visible light irradiation for living cell detection.The formation of TiO2/CdS heterojunction structure greatly enhances photocatalysis in visible light region by promoting separation of photogenerated electron-hole pairs.Additionally,the absorption in visible light of PEDOT further accelerates the electrode renewal.PEDOT coating provides a sensitive biosensing interface for electrochemical detection,and meanwhile prevents the cytotoxicity of CdS to cells.This allows electrochemical monitoring of nitric oxide release from living cells and subsequent visible light-induced electrode regeneration,demonstrating great potential of this renewable electrodes in biosensing.
Poly(3,4-ethylenedioxythiophene) TiO2/CdS nanocomposites Visible light Renewable electrode Nitric oxide Living cell
Huan-Huan Duo Jia-Quan Xu Yan-Ling Liu Zi-He Jin Xue-Bo Hu Wei-Hua Huang
Key Laboratory of Analytical Chemistry for Biology and Medicine,Ministry of Education,College of Chemistry and Molecular Sciences,Wuhan University,Wuhan 430072,China
国际会议
南京
英文
371-376
2016-12-23（万方平台首次上网日期，不代表论文的发表时间）