控制耐药性肠道病原菌、提高猪生长性能的可行方案:酶制剂、精油和1-单甘油酯
Antimicrobial resistance (AMR) represents a grave threat to both human and animal health.Antimicrobials are extensively used in pig production including active ingredients critically important for human medicine.Excessive consumption of antimicrobial may exert selective pressures on bacteria populations and speed up the spread of AMR.Moreover, new resistance mechanisms will likely to emerge in future as the recent discoveries of mcr-1 and mcr-2 genes has dramatically emphasized (S.Malhotra-Kumar, et al., 2016).The gene mcr-1 cause an important and rapid antimicrobial resistance and can be transferred between different types of bacteria.The gene was first identified in bacteria (Enterobacteriaceae)in South China, and since then has also been found in the EU and other regions.Micro-organisms resistant to a certain antibiotic may also be resistant to other antibiotics that share a mechanism of action or attachment.Such relationships, known as cross-resistance exist mainly between agents that are closely related chemically (e.g.polymyxin B and colistin, neomycin and kanamycin),but may also exist between unrelated chemicals (e.g.erythromycin-lincomycin).Micro-organisms may be resistant to several unrelated antibiotics.Use of one such antibiotic will therefore also select for resistance to the other antibiotics.
G.L.Alborali G.Tosi M.Parini V.Bontempo F.Foresti A.Paoli
Istituto Zooprofilattico Sperimentale della Lombardia e dellEmilia Romagna (IZSLER)-Brescia Istituto Zooprofilattico Sperimentale della Lombardia e dellEmilia Romagna (IZSLER)-Forli SILO SpA-Firenze Università degli studi di Milano-Milano GKL R&D-Bologna
国际会议
上海
中文
227-239
2016-10-20（万方平台首次上网日期，不代表论文的发表时间）