Association of Blood Pressure with Development of Metabolic Syndrome Components:a Five-Year Cohort Study in Beijing
Objective: Raised blood pressure (BP) is associated with the incidence of metabolic syndrome (MetS).It is unknown if subjects with different BP levels may develop certain components of MetS over time.We investigated the incidence of MetS relative to different levels of BP during a 5-year period in a Chinese population in Tongren Hospital, Beijing.Methods:During the period 2006-2011, we recruited 2 734 participants with no MetS, or self-reported type 2 diabetes, dyslipidemia, hypertension, or cardiovascular disease at baseline.Link analysis was used to identify the transitions of MetS components over time.Results: The incidence of MetS at follow-up was 9.74% for men and 3.21% for women in the group with optimal BP;10.29% and 7.22%, respectively, in the group with normal BP;10.49% and 10.84%, respectively, in the group with high-normal BP;and 14.48% and 23.21%, respectively in the group with high BP.The most common transition was from healthy to healthy in the groups with optimal or normal BP (22.06-49.25%), whereas in the high-normal BP group, 12.05-17.90% of subjects with raised BP returned to healthy status or stayed unchanged, while 13.79-21.43% of people with high BP tended to develop raised fasting glucose levels.Conclusions: The incidence of MetS grew in parallel with the increase in BP.People with optimal and normal BP levels were less susceptible to developing MetS over time, whereas abnormal BP seemed to be a pre-existing phase of MetS.High-normal BP was a crucial status for MetS prevention.
metabolic syndrome blood pressure link analysis cohort study
Da Huo Xia Li Wei Wang Lixin Tao Lei Pan Huiping Zhu Zhaoping Wang Dongning Chen Yanxia Luo Xiuhua Guo
School of Public Health, Capital Medical University, 100069 Beijing, China;Beijing Key Laboratory of Department of Integrated Early Childhood Development, 100020, Capital Institute of Pediatrics, Beiji Physical Examination Department, Beijing Tongren Hospital, Capital Medical University, 100730, Beiji
国际会议
北京
英文
93-103
2013-06-01（万方平台首次上网日期，不代表论文的发表时间）