Review of the computational models for the signaling pathway

摘要：

　　In the past few years,systems biology methods have been widely used to explore the mechanism of cancer.Various signaling pathways play the important role in cancer.And a large number of computational methods are used to model the signaling pathway.Here,we reviewed many existing mechanisms and modeling techniques,which are used to model different signaling pathways.Then we introduced the systematic workflow of a system biology approach and some fundamental analysis methods.Finally we discuss some known challenges in the process of modeling signaling pathways and what we should handle in our future work.

关键词： signaling pathway computational models systems biology

作者: Meijing Kong Chao Wang Le Zhang

作者单位: Computer and Information Science, Southwest University, Chongqing, China

会议类型: 国际会议

会议名称: 2016 2nd International Conference on Mechanical, Electronic and Information Technology Engineering(2016机械、电子和信息技术国际会议)

会议地点: 重庆

会议语种:英文

页码: 104-110

在线出版日期: 2016-03-21（万方平台首次上网日期，不代表论文的发表时间）