Identification of active ingredient of codonopsis cordifolioidea by n-butyl alcohol

摘要：

　　Current Codonopsis cordifolioidea products are mostly its crude extract,which is of low technology content and low added value,and studies on the active ingredients of Codonopsis cordifolioidea are very limited.To promote industrial development of Codonopsis cordifolioidea product and to increase its technology content,basic researches on this plant shall be enhanced,including identification of its original species,establishment of appropriate animal model,separation and tracking of the active components,clarification of the mechanism of its effect to replenish qi and nourish blood,and identification of its effective parts and active ingredients,thus to lay the basis for establishment of the standards for Codonopsis cordifolioidea as a medicine.This study seeks to isolate the active ingredients of Codonopsis cordifolioidea.Methods: 95% ethanol was used for initial crude extraction,the solution was further extracted with petroleum ether and n-butanol by chromatography,and the n-butanol portion was eluted by gradients of chloroform-methanol (98:2~70:30).Results and conclusion: three elution peaks were detected at 37min,1h10min,and 1h39min,and three components: E,F,G were identified.These results indicate that 3 active ingredients can be isolated from raw Codonopsis cordifolioidea material by n-butanol chromatography following soxhlet extraction.

关键词： Codonopsis cordifolioidea Active ingredients N-butyl alcohol Separation chromatography

作者: Yunpeng Luan Shuangqing Zheng Yanmei Li Qiming Wang

作者单位: College of Life Sciences,Southwest Forestry University China 650224 KPC Pharmaceuticals,Inc China

会议类型: 国际会议

会议名称: 2016 Internatioanl Conference on Engineering and Technology Innovations(ICETI-2016))2016年工程与技术创新国际会议

会议地点: 武汉

会议语种:英文

页码: 178-182

在线出版日期: 2016-03-25（万方平台首次上网日期，不代表论文的发表时间）