Sub-5 nm Lanthanide Doped ZrO2 Upconversion Nanoparticle for Protein Targeted Biomaging
Lanthanide-doped upconversion nanoparticles(UCNPs)are a promising new generation of imaging agents for bioimaging due to no auto-fluorescence,large penetration depth and non-blinking.In this paper an efficient ultra-small core-shell UCNP was synthesized using a hydrothermal method and a thermal decomposition procedure.A new inorganic host — ZrO2 was used for its low phonon energy and high absorption coefficient 1.The as-synthesized core shell nanoparticles has a diameter smaller than 5 nm.An aptamer was employed as a recognizer for protein recognition to implement the bioimaging.Therefore,the small and efficient core-shell nanoparticles was fabricated to achieve the single-proteins-targeted imaging.
Jing Liu Qiuqiang Zhan
Centre for Optical and Electromagnetic Research,South China Normal University Guangzhou 510006,China
国际会议
Progress in Electromagnetics Research Symposium 2014(2014年电磁学研究新进展学术研讨会)
广州
英文
2736-2740
2014-08-01（万方平台首次上网日期，不代表论文的发表时间）