Quantitative Evaluation of Interictal High Frequency Oscillations in Scalp EEGs for Epileptogenic Region Localization

摘要：

　　Electroencephalography is a commonly used tool for presurgical evaluation of epilepsy patients.In this paper, we present a quantitative evaluation of interictal high frequency oscillations (HFOs) in scalp Electroencephalographies (EEGs) for epileptogenic region localization.We process multichannel EEGs using time-frequency spectral analysis in order to detect HFOs in each EEG channel.Comparison between the results of time-frequency analysis and visual assessment is performed to verify the reliability of time-frequency analysis.Later,t-test and Pearson correlation analysis are performed to analyze the relationships between ictal HFOs and interictal HFOs.The high correlations between interictal and ictal HFOs imply that interictal HFOs, like ictal HFOs, are valuable in localizing the epileptogenic region.As a result, scalp interictal HFOs are valuable in epileptogenic region localization for presurgical evaluation of epilepsy patients.It holds great potential for reducing the long delay before patients can be referred for surgery.

关键词： High frequency oscillations Scalp EEGs Epileptogenic region localization

作者: Yaozhang Pan Cuntai Guan How-Lung Eng Shuzhi Sam Ge Yen ling Ng Derrick Wei Shih Chan

作者单位: Institute for Infocomm Research, Agency for Science, Technology and Research (ASTAR),1 Fusionopolis Department of Electrical and Computer Engineering, National University of Singapoire,Singapore 11757 KK Womens and Childrens Hospital, 100 Bukit Timah Road,Singapore 229899, Singapore

会议类型: 国际会议

会议名称: The Seventh International Conference on Intelligent System and Knowledge Engineering, ISKE 2012/The 1st International Conference on Cognitive System and Information Processing, CSIP 2012(第七届智能系统与知识工程国际会议/第一届认知系统与信息处理国际会议)

会议地点: 北京

会议语种:英文

页码: 419-427

在线出版日期: 2012-12-15（万方平台首次上网日期，不代表论文的发表时间）