On bistability in genetic double-negative feedback loop with positive autoregulations

摘要：

　　This paper focuses on bistability in a class of simplified double-negative feedback loop with positive autoregulations(DNFLPAs).The existence criteria of multiple equilibriums is established and the stability conditions are derived for each equilibrium.The effect of each biochemical parameters on bistability is explained.At last,several numerical simulations are carried out to deepen our analysis.

关键词： Multistability Double-negative feedback loop Positive autoregulation Genetic Regulatory Networks

作者: LING Guang HE Ding-Xin GUAN Zhi-Hong ZHANG Xian-He ZHAN Xi-Sheng

作者单位: College of Automation,Huazhong University of Science and Technology,Wuhan 430074,P.R.China College of Mechatronics and Control Engineering,Hubei Normal University,Huangshi 435002,P.R.China

会议类型: 国际会议

会议名称: The 33th Chinese Control Conference第33届中国控制会议

会议地点: 南京

会议语种:英文

页码: 2872-2876

在线出版日期: 2014-07-28（万方平台首次上网日期，不代表论文的发表时间）