Preparation and Properties of Silicon-Zinc-Glycerol Hydrogels

摘要：

　　A number of silicon-zinc-glycerol hydrogeis resistant to syneresis was synthesized according to the sol-gel methodology.The optimum composition of silicon-zinc-glycerol hydrogel for preclinical trials was determined.It has been established that this gel is non toxic.The wound-healing and antimicrobial properties of the hydrogei were studied.The experimental results showed that the studied silicon-zinc-glycerol hydrogel can be recommended for the application as local and ex ternal pharmaceutical formulations and as the substrate for the pharmaceutical compositions with wound-heal ing, regenerative and antimicrobial activity.

关键词： Silicon-zinc-glycerol hydrogels Wound healing Antimicrobial activity

作者: I.N.Shtanko A.N.Bondarev E.V.Shadrina T.G.Khonina O.N.Chupakhin

作者单位: Postovsky Institute of Organic Synthesis,Russian Academy of Sciences (Ural Branch),22/20 S. Kovalevskoy/Akademicheskaya St.,620041 Ekaterinburg,Russian

会议类型: 国际会议

会议名称: The 12th China-Russia Symposium on Advanced Materials and Technologies(第十二届中俄双边新材料新工艺国际会议)

会议地点: 昆明

会议语种:英文

页码: 235-237

在线出版日期: 2013-11-19（万方平台首次上网日期，不代表论文的发表时间）