Potential Strategies Based on Cellular Mechanisms to Reduce Oxidative Stress in Obesity

摘要：

　　The capital factor in tiie etiology of obesity and obesity-related metabolic syndrome seems to be oxidative stress.The generation of oxidative stress in accumulated fat is indicated by tiie increasing formation of ROS and elevated secretion of adipocytokines.ROS overwhelmingly is associated witii mitochondria,NADPH oxidase,as well as xanthine oxidase.Imbalance production of adipocytokines is closely related to tiie activating stress responsive patiiways in adipose tissue.Approaches to tackle high oxidative stress in obesity should thus be tiie suppression of oxidative stress based on the corresponding cellular or molecular mechanism.This paper addresses oxidative stress and potential interventions to lower oxidation.Oxidative stress can be reduced by caloric restriction,physical exercise,tiiermal therapy or infrared Ireatoient,and may be corrected by improving antioxidant supplementation.

关键词： Obesity Oxidative stress Adipose Antioxidant

作者: Xiao-Fen Lin Yi Li Hang-Mei Leung

作者单位: Institute of Textiles and Clothing,The Hong Kong Polytechnic University,Hung Hom,Hong Kong,China;Gua Department of Health Technology and Informatics,The Hong Kong Polytechnic University,Hung Hom,Hong K

会议类型: 国际会议

会议名称: 第六届纺织生物工程及信息国际会议(The 6th Textile Bioengineering and Informatics Symposium )(TBIS2013)

会议地点: 西安

会议语种:英文

页码: 190-199

在线出版日期: 2013-09-26（万方平台首次上网日期，不代表论文的发表时间）