Platelet adhesion on the silk fibroin material surface

摘要：

　　Silk fibroin (SF) has good biocompatibility and has been used to construct small caliber artificial blood vessels.As a vascular graft, the antithrombogenicity is the first important performance.The aim of this study was to evaluate the anticoagulant property of polyethylene glycol diglycidyl ether (PEG-DE) crosslinked and ethanol treated SF materials by investigating the platelet adhesion.Dacron and PTFE were parallel studied as the controls.Results showed that: the platelet adhesion ratios on the ethanol treated SF films were significantly lower than that on the Dacron and PTFE; the platelet adhesion ratios on the PEG-DE crosslinked SF films were higher than that on the ethanol treated SF films and slightly increased with increasing the proportion of the PEG-DE.But the platelet adhesion ratios on all of the PEG-DE crosslinked SF films were significantly lower than that on the controls.

关键词： Silk fibroin PEG-DE Platelet adhesion

作者: Dan Sun Yali Wei Yu Wang Jiannan Wang

作者单位: College of Textile and Clothing Engineering,Soochow University,Suzhou 215021,China

会议类型: 国际会议

会议名称: The 8th China International Silk Conference (ISC2013)、The 4th Asian Protective Clothing Conference(APCC2013)and Eco-Friendly Textile Dyeing and Finishing Conference( 第八届中国国际丝绸会议、第四届亚洲防护服会议暨环保纺织染整会议)

会议地点: 苏州

会议语种:英文

页码: 136-139

在线出版日期: 2013-09-09（万方平台首次上网日期，不代表论文的发表时间）