Surface Characterization of Poly(DL-lactide-co-glycolide)(PLGA)Membranes Fabricated by the Various Methods for Biomedical Applications

摘要：

　　A systematic study on molecular structure of Poly(DL-lactide-co-glycolide) (PLGA) films by the methods of being chemically immobilized onto self-assembled monolayers (SAMs) and spin coating using Fourier transform infrared spectroscopy (FTIR), sum frequency generation (SFG) vibrational spectroscopy is reported.Especially, a surface sensitive second order nonlinear optical technique, SFG vibrational spectroscopy, was applied to study molecular structure on PLGA films.It is shown that the more chemical groups of PLGA thin films with being chemically immobilized have orientation than that of PLGA films made by spin coating on the basis of SFG vibrational spectroscopy data.The characterization of the other analytical techniques indicates similar results.This work will be an important step for future biomaterials design and understanding biosensors, biocompatibility and biomacromolecule (e.g.proteins and peptides) activity.

关键词： PLGA self-assembled monolayers biomaterials

作者: Fujuan Liu

作者单位: National Engineering Laboratory for Modem Silk,College of Textile and Clothing Engineering,Soochow University,199 Ren-Ai Road,Suzhou 215123,P.R.China

会议类型: 国际会议

会议名称: The 8th China International Silk Conference (ISC2013)、The 4th Asian Protective Clothing Conference(APCC2013)and Eco-Friendly Textile Dyeing and Finishing Conference( 第八届中国国际丝绸会议、第四届亚洲防护服会议暨环保纺织染整会议)

会议地点: 苏州

会议语种:英文

页码: 333-336

在线出版日期: 2013-09-09（万方平台首次上网日期，不代表论文的发表时间）