Aptamer Biosensors for Microorganism Detection

摘要：

　　Aptamers are single-stranded oligonucleotides that bind with high specificity and affinity to a target molecule.Aptamer-based biosensors have become a new class of biosensors,which utilized aptamers as highly selective recognition elements as a result of good performance in the capture of target analytes.In this study,aptamer was used as an recognition element of biosensor,and was integrated to microarray chip to realized the detection of L.achidophilus.The fluorescence and transmission image of bacterial cells were obtained in different times magnification field.The results demonstrated that the aptamer biosensor based on microarray chip can be used to detect L.achidophilus by means of FITC labeled bacterial cells.

关键词： biosensor microorganism detection Lactobacillus acidophilus

作者: Congxiao Zhang Xuefei Lv Hong Qing Lina Geng Yulin Deng

作者单位: School of Life Science Beijing Institute of Technology Beijing 100081, China

会议类型: 国际会议

会议名称: 2013 ICME International Conference on Complex Medical Engineering(2013 ICME复合医学工程国际会议)

会议地点: 北京

会议语种:英文

页码: 254-259

在线出版日期: 2013-05-25（万方平台首次上网日期，不代表论文的发表时间）