Relativity Analysis between Resting-State fMRI Signal and Tumorous Possibility of Brain Tissues
fMRI is widely used to investigate the spontaneous activity of the brain.In this paper,a quantitative analysis method is proposed to describe the relationship between the BOLD features of resting-state fMRI and the tumorous growth of brain tissues.In our method,a map of tumorous possibility degree is detected from tissues structural images of MRI and coregistered into the functional space.After extracting the BOLD features,further analysis is done to reveal the relationship between functional signal and tumor growth.The average value of BOLD signal is found as a significant feature of tumorous tissues and resultantly presents a positive correlation with the degree of tumorous possibility.The same method is also applied in the analysis of the most commonly used BOLD features include ALFF and ReHo.In the results the two features show a negative correlation with the tumorous possibility degree.The method proposed in our study is based on multimodal signal combination of tissues structure and functional features.It should be a valuable method and serve as a basic understanding for explaining how the tumor influences brain function and further for rebuilding the functional network.
resting-state fMRI brain tumor BOLD feature tumorous possibility degree relationship
Xue Wang Weibei Dou Yinyan Wang Tao Jiang
Tsinghua National Laboratory for Information Science and Technology Dept. of Electronic Engineering, Beijing Tiantan Hospital, Capital Medical University, Beijing, P. R. China Jean-Marc CONSTANS Neuror
国际会议
2013 ICME International Conference on Complex Medical Engineering(2013 ICME复合医学工程国际会议)
北京
英文
388-393
2013-05-25（万方平台首次上网日期，不代表论文的发表时间）