A Review on Gene Delivery System of Layered Double Hydroxide

摘要：

　　This paper aims to provide a concise review on the study of a gene delivery system with layered double hydroxides (LDH) as carrier.The issues, such as preparation and cytobiology effect of LDH-DNA hybrids, and the release mechanism of DNA from LDH-DNA complex, were discussed in detail.For achieving a ideal cell transfection efficiency, it would be prospective to improve both the intercalation effect of giant DNA, such as plasmid DNA and long chain DNA fragments, and the gene transfection technique of small DNA fragment.

关键词： Layered Double Hydroxides Gene Transfer LDH-DNA Complex System

作者: Li-e DONG Guo-jing GOU Jie HUANG Yue SUN Bing XUE

作者单位: Medical chemistry department,School of Basic Medical,Ningxia medical university,yinchuan 750004

会议类型: 国际会议

会议名称: 2012 China Functional Materials Technology and Industry Forum(2012中国功能材料科技与产业高层论坛)(CFMTIF2012)

会议地点: 昆明

会议语种:英文

页码: 533-539

在线出版日期: 2012-11-09（万方平台首次上网日期，不代表论文的发表时间）