Simulating FAS-Induced Apoptosis by Using P Systems
In contrast to differential equations: P systems are an unconventional model of computation which takes into consideration the discrete character of the quantity of components and the inherent randomness that exists in biological phenomena.The key feature of the P systems is their compartmentalized structure which represents the heterogeneity of the structural organization of the cells,and where one can take into account the role played by membranes in the functioning of the system,for example,signalling at the cell surface: selective uptake of substances from the media.diffision across different compartments,etc.We show here that the P systems can be a reliable tool for Systems Biology and could even outperform in some cases the current simulation techniques based on differential equations.We will also use a strategy that is based on the well known Gillespies algorithm.But running on more than one compartment and so it will be called Multi-commpartmental Gillespie Algorithm.
Smitha Cheruku Andrei P(a)un Francisco J.Romero-Campero Mario J. Pérez-Jiménez Oscar H.Ibarra
Department of Computer Science/IfM：Louisiana Tech University,P.O. Box 10348,Ruston,LA 71272 Department of Computer Science and AI,University of Sevilla Avda. Reina Mercedes s/n 41012,Sevilla,S Department of Computer Science,University of California - Santa Barbara CA 93106,USA
国际会议
武汉
英文
71-81
2006-09-18（万方平台首次上网日期，不代表论文的发表时间）