In Vitro Inhibitory Effects of Inonotus obliquus Extracts on Mushroom Tyrosinase

摘要：

　　The mushroom Inonotus obliquus (Ach.ex Pers.) Pilát has been traditionally used as a folk medicine in Russia,Poland and most of the Baltic countries.In this study,the purpose was to elucidate inhibitory kinetics on mushroom tyrosinase activities of Inonotus obliquus.Four extracts were evaluated for inhibitory effects on mushroom tyrosinase.The petroleum ether and n-butanol extract exhibited significant inhibitory potency.While the former was identified as a noncompetitive tyrosinase inhibitor,the later was a mixed-type inhibitor.The monophenolase activity IC50 values were estimated to be 0.93mg/ml and 0.87mg/ml,respectively.In the contrary,the ethyl acetate extract contributed to the progress of mushroom tyrosinase activities,mainly containing inotodiol,trametenolic acid by HPLC analysis.However,the aqueous extract had no effects.

关键词： Inonotusobliquus Tyrosinase HPLC Inotodiol Trametenolicacid

作者: ZHENGFEI YAN CHANGTIAN LI YU LI

作者单位: Engineering Research Center of Edible and Medicinal Fungi, Ministry of Education, Jilin Agriculture University,Changchun 130118, China

会议类型: 国际会议

会议名称: The 7th International Medicinal Mushroom Congerence(第七届国际药用菌大会(IMMC7)

会议地点: 北京

会议语种:英文

页码: 76-86

在线出版日期: 2013-08-26（万方平台首次上网日期，不代表论文的发表时间）