Dynamical behaviour of an anti-HBV infection therapy model with time-delayed immune response
Mathematical models have been used to understand the factors that govern infectious disease progression in viral infections.In this paper,based on the standard mass action incidence,an anti-HBV therapy model with time-delayed immune response is set up.The time-delay is used to describe the period of time for antigenic stimulation to generate CTLs.The globally asymptotically stable analysis of the infection-free equilibrium is given in the paper.Some conditions for Hopf bifurcation around endemic equilibrium to occur are also obtained by using the time delay as a bifurcation parameter.
Mathematical model HBV Immune Therapy
Xinjian Zhuo Yongmei Su
School of Sciences,Beijing University of Posts and Telecommunications,Beijing, China School of Mathematics and PhysicsUniversity of Science and Technology Beijing,Beijing, China
国际会议
7th International Conference on Systems Biology(第7届计算系统生物学国际研讨会)(ISB2013)
安徽黄山
英文
86-91
2013-08-22（万方平台首次上网日期，不代表论文的发表时间）