Identification and Genetic Characterization of Bovine Viral Diarrhea Virus Genotype 2 Strains Isolated in Pigs in China

摘要：

　　Twelve bovine viral diarrhea virus 2 (BVDV-2)strains were screened and isolated from sick pigs with CSF-like symptoms.Homology comparison showed that the E2 genes of the twelve isolates were highly conserved.The full length genome of the one of the BVDV-2 isolates (named as SH-28),which showed a noncytopathic effect in MDBK cell cultures and strong reactivity with MAb Bz-53 raised against BVDV-2,was sequenced.The genome of SH-28 comprises 12,279 nucleotides and contains a large ORF beginning at nucleotide 386 and ending at nucleotide 12073.Genomic comparison and phylogenetic analyses showed that SH-28 fall into BVDV-2 subtype and was most similar to XJ-04 isolate (bovine BVDV-2),but was genetically divergent from ZM-95 (pig BVDV-1).

作者: Tao Jie Wang Yin Wang Juan Wang Jianye Zhu Guoqiang

作者单位: College of Veterinary Medicine,Yangzhou University,Yangzhou 225009,China

会议类型: 国际会议

会议名称: XVIth International Congress on Animal Hygiene(第十六届动物卫生国际会议(ISAH 2013))

会议地点: 南京

会议语种:英文

页码: 138-139

在线出版日期: 2013-05-05（万方平台首次上网日期，不代表论文的发表时间）