New Opportunity of Mycotoxin Elimination
It is generally agreed that farm animals should be protected against the adverse effects of mycotoxins.Of the available opportunities,recently the use of microorganisms for biotransformation of mycotoxins has been mcreasing.Detoxa Plus has been specially developed for enzymatic decomposition of mycotoxins in animal feeds via its active germ component.The present paper summarise the main findings of three experiments that either had been published *** (Kutasi,J.,Papp Z.,Jakab.L.,Brydl,E.,Rafai P.: Deactivation of T-2 toxin in broiler ducks by biotransformation.J.Appl.Poult.Res..2012.21.13-20.),being published * * (Rafai P.,Papp Z.,Jakab 1.: Biotransformation of trichothecenes alleviates the negative effects of T-2 toxin in pigs.Acta Vet.Hung.AVH 116/2012)or submitted for publication * (Bata (A),Vanyi A.,Glávits,R.,Brydl E.,Rafai P.: Alleviation of the oestrogenic effect of zearalenone in pigs by a feed additive.Acta Vet.Brno,2013).Our experiments with growing pigs demonstrated that T-2 toxin impairs feed intake and weight gain of growing pigs at as low as 0.3 and 0.5 mg/kg feed concentration.The feed additive used in the present experiment improved the feed intake and daily weight gain of pig significantly.Although parameters of improved feed consumption and weight gain numerically lagged behind those of the control pigs the gap between data of experimentally treated pigs and controls was small and statistically not significant.Another experiment provided data on the preventive capacity of Detoxa Plus against oestrogen mimetic Zearalenone.The positive effects included the prevention of ovarian and uterine enlargement,beneficial effects on the histopathological scores of the ovaries.uterus and vagina and reduced concentration of Zea and its metabolites in the liver.In experiments with broiler ducks the adverse effect of 0.6 ppm dietary T-2 toxin was fully counteracted by the feed additive in terms of daily weight gain,cumulative daily weight gain and live weight at exsanguinations.T-2 toxin depressed the blastogenic response of lymphocytes to non-specific mitogens (ConA and PHA)which was fully prevented by the feed additive.
Rafai P Papp Z Glávits R Bata (A)
ISZIE University,Faculty of Veterinary Science,Budapest,Hungary Central Veterinary Institute,Budapest,Hungary Bata LTD,Hungary
国际会议
XVIth International Congress on Animal Hygiene(第十六届动物卫生国际会议(ISAH 2013))
南京
英文
336-338
2013-05-05（万方平台首次上网日期，不代表论文的发表时间）